OSTEO-PHARMA: BONE THERAPEUTICS
LATEST NEWS
Osteo-Pharma BV develops novel medication and medical devices for orthopedic and dental applications for the local treatment of bone fractures and bone defects. Osteo-Pharma’s technology platform is based on applying local sustained delivery of low molecular weight compounds that enhance bone formation while simultaneously inhibiting bone resorption. Osteo-Pharma was founded in June 2014 and applies novel technology to deliver pharmaceuticals locally near to a bone fracture or bone defect. By encapsulating pharmaceuticals in a biodegradable carrier sustained release of pharmaceuticals over a 6-8 week period is achieved. During this period bone growth is enhanced and bone resorption is inhibited resulting in a net effect of bone growth. This technology is now in development to improve the healing of bone fractures, bone defects and for the treatment of osteoarthritis. In addition, Osteo-Pharma is developing a novel coating for dental and orthopedic implants to improve osseo-integration and to prevent implant loosening.
Successful Preclinical Dental defect study Demonstrates Enhanced Bone Regeneration Properties of OsteoActivator coated collagen membranes
Osteo-Pharma, a Dutch Life Sciences company developing novel pharmaceuticals and medical devices to improve the local healing of bone fractures and defects, today has announced that it has successfully completed a large preclinical study in mini-pigs, which shows its OsteoActivator coated collagen membranes to effectively promote new bone formation.
OSTEOACTIVATORTM TECHNOLOGY PLATFORM
Osteo-Pharma’s OSTEOACTIVATORTM technology is based on the use of EMA and FDA approved low molecular weight pharmaceuticals. By encapsulation in a biodegradable carrier sustained release of these pharmaceuticals over a 6-8 week period is obtained. During this period osteoblast activity is enhanced and osteoclast activity is inhibited resulting in a net shift towards the formation of new and stronger bone. Upon release of the therapeutics (after 6-8 weeks) bone remodeling will continue normally and, hence, the newly formed high quality bone will remain intact. Furthermore, the biodegradable carrier will degrade within the next few weeks eliminating the need for surgery to remove the carrier. read more
BONE FRACTURE FACTS
Bone fracture healing results in regeneration of bone at the fracture site resulting in bone tissue that has similar biomechanical competence as before the injury. Fractures, or broken bones, are extremely common. On average, every person will experience two broken bones over the course of a lifetime.
read more